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No, they are managed through the Mac plugin manager in the Office Scan admin console, and through the separate (local) Linux Server Protect console, respectively.
The client is still protected from viruses whose signatures exist locally to the client. Please follow the directions found here: https://esupport.trendmicro.com/solution/en-US/1035208You will need to download this executable to complete the above instructions. In order for the clients to reach the Office Scan server, you'll need to allow traffic to 184.108.40.206 and 220.127.116.11 over port 443 (egress).
If scanning is required, the file information is sent to Smart Protection Server to be verified against the Smart Scan Pattern file.
When anti-malware is using conventional scanning model, the file is verified against the local virus pattern file.
When anti-malware is enabled and is configured to use Smart Scanning, what happens is that a file scanning is verified against a local pattern file (Smart Scan Agent Pattern) this contains half of the virus signature.
The file hash signature is then compared against the BF pattern which also resides locally, the BF pattern will determine if the file hash signature needs to be sent to Smart Protection Server.
When you install any of the Linux products, you will be prompted for three items, one of which is the activation key.